Autologous stem cell transplant
Autologous Stem Cell Transplant in Hyderabad
What is an Autologous Stem Cell Transplant?
The process of an autologous stem-cell transplant is an medical procedure where patients’ stem cells that are healthy are harvested, stored and then reintroduced into the body following high-dose chemotherapy. This method is typically utilized to regenerate bone marrow which has been damaged by intense radiation therapy or chemotherapy.
Because the stem cells originate from the same person so it is no chance that there is donor incompatibility or graft-versus host disease. It is a secure and efficient way to help the healing process of certain cancers and blood diseases.
Why Choose an Autologous Transplant?
If aggressive treatment for cancer is required, the bone marrow is often subject to significant damage. In such instances the autologous transplant can allow doctors to:
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Kill cancerous cells efficiently with high-dose chemotherapy.
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Replace healthy blood-forming cells by using the patient’s stored stem cells.
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Beware of complications arising from rejection of donor cells or immune incompatibility.
Conditions Commonly Treated
Stem cell autologous transplants are often suggested for patients with
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Multiple Myeloma
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Hodgkin’s Lymphoma
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Non-Hodgkin’s Lymphoma
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Acute or persistent plasma cell Disorders
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Some Solid tumors in certain instances
Step-by-Step Process
1. Mobilization of Stem Cells
The use of medicines such as growth factors are used to increase the flow of stem cells from bone marrow into the bloodstream.
2. Stem Cell Collection (Apheresis)
The blood is drawn through a vein, then passed through a machine which is able to separate and gather stem cells and the remainder is then returned back to the human body.
3. Cryopreservation
The stem cells collected are stored in a freezer with an anti-bacterial preservative. They are stored until transplantation is required.
4. Conditioning Therapy
The high doses of chemotherapy or radiation are administered to destroy cancerous cells, and to prepare for stem cell injection. The process can cause short-term side effects like nausea, fatigue, and infections due to a lack of immunity.
5. Stem Cell Infusion
The thawed stem cells get infiltrated through a vein similar to was a blood transfusion. They are transported into the bone marrow to begin to produce the healthy cells of blood.
Recovery and Monitoring
Following transplantation, patients will be closely monitored for
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Infections
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Low blood count
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Organ function
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Treatment response
Recovery can take weeks to a few months. Regular check-ups as well as blood tests and medications to support recovery are essential in this stage.
Benefits of Autologous Stem Cell Transplant
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Lower chance of rejection by the immune system
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Accelerate recuperation of counts in blood
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There is no need to conduct an online search for donors
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Multiple cancers
Autologous Stem-Cell Transplant in Hyderabad with expert care
At our modern transplant center located in Hyderabad we are specialized in autologous bone-marrow and stem cells transplants under the guidance of Dr. Padmaja Lokireddy, an experienced doctor of hematology and transplants. We offer a thorough evaluation as well as safe collection of cells and storage, as well as individualized treatment for each patient.

About the Doctor
Dr. Padmaja Lokireddy is a highly respected Hemato Oncologist, Bone Marrow & Stem Cell Transplant Surgeon with years of experience in the field. She earned her postgraduate degree in internal medicine from the prestigious Manipal Academy of Higher Education and continued her studies and worked in the UK for about 13 years.



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Frequently Asked Questions about Bone Marrow Failure
The words "bone marrow transplant" and "stem cell transplant" are sometimes used together, which might be confusing. Both names refer to the same procedure. All transplants that used to treat blood or bone marrow cancers contain stem cells.
Bone marrow transplants replace unhealthy stem cells with healthy ones to cure cancers and other blood and bone marrow disorders. BMT is most often used to treat leukemia and lymphoma patients.
Patients whose bone marrow has been damaged by chemotherapy or radiation treatment may benefit from BMT. It also helps those with conditions that cause their bone marrow to stop working.
Yes. Irrespective of the patient's age, a bone marrow transplant is generally the same process. For our younger patients, we make certain changes, such as sedating them prior to the transplant to reduce their anxiety.
Thrombocytosis is often detected through routine blood tests. If your platelet levels are higher than normal, it is important to consult with your doctor to determine the underlying cause.