Pediatric Thrombocytopenia
What is Thrombocytopenia in Children?
Thrombocytopenia is a condition characterized by a deficient blood platelet count. The role of platelets is to clot and stop bleeding after injuries happen. For children, this issue may be caused by a variety of reasons including infections and immune system-related responses.
Although some children do not exhibit obvious signs while others might show indications of bruising or bleeding that need medical attention and treatment. The identification of the reason is crucial to determine the best treatment plan.
Causes of Thrombocytopenia in Children
The thrombocytopenia of children may be permanent or chronic and its causes may be a variety of things:
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Viral infections (e.g., Epstein-Barr virus, cytomegalovirus, dengue)
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Immune Thrombocytopenia (ITP) – occurs when the immune system is mistakenly attacking platelets
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Bone marrow diseases that impact the production of blood cells
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Autoimmune illnesses
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Medicines that affect the production of platelets, or even the survival of platelets
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Genetic disorders that affect blood cells
In many instances, particularly when it comes to ITP or post-viral, the condition will not get better and improves with time.
Common Symptoms
The severity of the symptoms varies in the extent of low platelet count. The most common symptoms are:
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A few bruising slashes without obvious trauma
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Tiny purple or red spots on the skin (petechiae)
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Nasal bleeding that is frequent or for a long time
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Gums bleeding, particularly after brushing your teeth
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In the urine or in stool, there is blood.
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The menstrual cycle is very heavy during adolescent girls
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In rare instances, there may be bleeding from the internal organs or hemorrhage
It is imperative to seek prompt medical attention in order to avoid serious complications particularly if bleeding continues or unprovoked.
Diagnosis
To identify thrombocytopenia A pediatric hematologist will be able to:
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Complete Blood Count (CBC): Confirms low levels of platelets
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Blood smear outside Examines the form and amount of blood cells
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Bone Marrow Test (in certain cases) is used to determine if the production is affected
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Panels of viral and immunological testing: Identifies underlying triggers like the presence of immune reactions or infections
Treatment Options
The treatment is based on the extent and cause of thrombocytopenia.
Observation
In mild cases with no active bleeding, particularly if the cause is a viral illness or ITP following-up and observation could be all that is required. Children recover with no specific treatment.
Medications
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The use of corticosteroids to stop immune-related destruction of platelets
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Intravenous Immunoglobulin (IVIG) for faster increase in platelets in immune cases.
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Anti-inflammatory drugs or thrombopoietin Agonists to treat chronic, or even refractory patients
Transfusions
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Transfusions of platelets could be offered in the event of severe bleeding or prior to surgery
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Transfusions of red blood cells when anemia is present
Managing Bleeding
Aidive measures like antifibrinolytics or nasal packing for nosebleeds, and staying clear of medications such as aspirin and ibuprofen can aid in preventing or control bleeding.
Long-Term Outlook
In the majority of pediatric cases thrombocytopenia is a temporary condition and disappears completely. Children with immune thrombocytopenia typically disappears within six months. If children suffer from primary or chronic causes a long-term treatment by an pediatric hematologist is crucial.
With the right diagnosis and treatment Children with thrombocytopenia are able to lead active, healthy lives.
Why Choose Expert Care?
If your child has been diagnosed with thrombocytopenia it is important to seek treatment from specialists who are familiar with pediatric blood conditions. A thorough evaluation, individualized treatment and continuous monitoring are essential to treating this condition efficiently.
About the Doctor
Dr. Padmaja Lokireddy is a highly respected Hemato Oncologist, Bone Marrow & Stem Cell Transplant Surgeon with years of experience in the field. She earned her postgraduate degree in internal medicine from the prestigious Manipal Academy of Higher Education and continued her studies and worked in the UK for about 13 years.
